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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FREM3 All Species: 12.42
Human Site: S1609 Identified Species: 39.05
UniProt: P0C091 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P0C091 NP_001161707 2135 237764 S1609 L I Y K H D G S E T T E D S F
Chimpanzee Pan troglodytes XP_517461 2289 255014 G1762 L I S Y K H D G S E T T E D S
Rhesus Macaque Macaca mulatta XP_001092507 2276 253244 G1749 M I S Y K H D G S E T T E D S
Dog Lupus familis XP_543127 3169 350410 T1606 I S Y R H D G T E S S E D S F
Cat Felis silvestris
Mouse Mus musculus Q5H8B9 2123 234980 S1601 L I Y C H D G S E T S K D S F
Rat Rattus norvegicus Q00657 2326 251891 R1688 L L S S S P A R D L A A T L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417087 3168 351300 T1605 I S Y K H D G T E S V E D S F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796581 2335 258813 A1761 L T V V I K D A K D G V C K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.2 88.7 39.3 N.A. 68 20 N.A. N.A. 39.7 N.A. N.A. N.A. N.A. N.A. N.A. 27.9
Protein Similarity: 100 92.6 90.9 49.8 N.A. 80.1 35.7 N.A. N.A. 50.4 N.A. N.A. N.A. N.A. N.A. N.A. 45.2
P-Site Identity: 100 20 13.3 60 N.A. 80 6.6 N.A. N.A. 66.6 N.A. N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 26.6 26.6 93.3 N.A. 93.3 20 N.A. N.A. 86.6 N.A. N.A. N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 13 13 0 0 13 13 0 0 13 % A
% Cys: 0 0 0 13 0 0 0 0 0 0 0 0 13 0 0 % C
% Asp: 0 0 0 0 0 50 38 0 13 13 0 0 50 25 0 % D
% Glu: 0 0 0 0 0 0 0 0 50 25 0 38 25 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 % F
% Gly: 0 0 0 0 0 0 50 25 0 0 13 0 0 0 0 % G
% His: 0 0 0 0 50 25 0 0 0 0 0 0 0 0 0 % H
% Ile: 25 50 0 0 13 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 25 25 13 0 0 13 0 0 13 0 13 0 % K
% Leu: 63 13 0 0 0 0 0 0 0 13 0 0 0 13 0 % L
% Met: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 13 0 0 0 13 0 0 0 0 0 0 0 % R
% Ser: 0 25 38 13 13 0 0 25 25 25 25 0 0 50 38 % S
% Thr: 0 13 0 0 0 0 0 25 0 25 38 25 13 0 0 % T
% Val: 0 0 13 13 0 0 0 0 0 0 13 13 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 50 25 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _